The role of rotavirus associated with pediatric gastroenteritis in a general hospital in Lagos, Nigeria
 /  The role of rotavirus associated with pediatric gastroenteritis in a general hospital in Lagos, Nigeria

The role of rotavirus associated with pediatric gastroenteritis in a general hospital in Lagos, Nigeria

Philip Ifesinachi Anochie, Edwina Chinwe Onyeneke, Emmanuel Osaretin Asowata, Ebelechukwu Afocha, Anthony Chidiebere Onyeozirila, Angelina Chinyere Ogu, Bestman Chukwuemeka Onyeneke

Abstract
Introduction: Bacterial, viral and parasitic agents have been implicated and confirmed as
causative agents of gastroenteritis in children with ages below 5 years old. The major role of rotavirus as
causative agent is not widely recognized within the public health community, particularly in developing
countries. This study examined the role of rotavirus as a causative agent of childhood gastroenteritis in
infants and young children below 5 years of age in a General Hospital in Lagos, Nigeria.
Methods: Parents and caregivers of children admitted to the hospital were interviewed using a
structured questionnaire. Viral RNA was extracted from the stool samples collected and analyzed using
RT-PCR for genotyping and agarose gel electrophoresis for identification of rotavirus electrophoretypes.
Results: Out of the 71 samples analyzed, 16 (22.5%) were positive for rotavirus. A total of 12
(75%) males and 4 (25%) females were positive for rotavirus gastroenteritis with most cases (7, 43.8%)
distributed to the 13-24 months age group, followed closely by the 1-6 months age group, with 6 cases,
37.5%. Rotavirus G2 genotype was the most prevalent strain in the hospital (10 patients, 62.5%) followed
by G1 (6 patients, 37.5%). These were the only rotavirus genotypes detected in the hospital.

Journal Article
PDF, 295.5 KB
Creative Commons LicenseCreative Commons license
Biological Sciences
Microbiology
Rotavirus, gastroenteritis, children.
Christian Bassey
18th April, 2018
18th April, 2018
http://oer.mciu.edu.ng/wp-content/uploads/2015/04/Anochie-et-al.-GERMS-2013.pdf


Staff Profile Download

MICHAEL AND CECILIA IBRU UNIVERSITY

Ibru Village
Agbarha – Otor
Ughelli North
Delta State
Nigeria

Admissions

CONNECT WITH US

Registry