Monday Abel Otache and Godwin Kparobo Agbajor
Herbal consumption has been on the increase in recent time, growing concern in its usage with regards to safety in terms of its toxicity cannot be overemphasized. The leaves of Neem (Azadirachta indica) commonly known in Nigeria as ‘’Dogonyaro’’ were collected from three major locations in Otukpo Local Government Areas of Benue State, Nigeria. The sites were designated the depicting code of O Mr (Market Road),O Ar (Adoka road) and O Ur (Upu Road). The experiment was carried out in the Department of chemistry Benue State University Makurdi.Reflux extraction was carried out using 70% methanol as extraction solvent standard analytical methods were used to determine the phytochemical content, while their proximate compositions were determined by methods described by A.O.C.A and their heavy metal contamination were determined using Atomic Absorption spectrophotometer (AAS). The results showed that the proximate composition of Neem leaves ranged from (12.10 to 14.30) %, (3.88 to 4.03) %, (1.22 to 4.04) %, (2.89 to 3.18) % and (9.25 to 10.86) % for Moisture, Ash, Protein, Fat and Fibre respectively. The concentrations of analyzed heavy metals along all the collection locations, ranged from (0.09 to 0.12) mg/100g Zn; (0.07 to 0.13) mg/100g Fe; ( 0.07 to 0.12) mg/100g Mn; (0.12 to 0.42) mg/100g Mg; 0.02 mg/100g Pb for O MR , with O MR recording the highest value across all the collection locations, while Pb for collection cite O AR and O UR were below detectable limit. The phytochemical composition reveals the ranes of values; (0.53 to 1.12) %, (0.92 to 1.94) %, (4.53 to 6.23) %, (1.85 to 3.96) % and (0.18 to 1.21) % for Tannin, Saponin, Flavonoid, Alkaloid and Hydrogen Cyanide respectively. The result from this study reveals that the plant can be used for medicinal purposes as its heavy metal composition falls within acceptable level recommended by WHO, hence will pose no harmful effect to human health when administered.
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Keywords: Metals, Minerals, Composition, Collection site.
18th April, 2018
18th April, 2018